품명 UltraGRO™-Advanced (Research-Grade)
규격 50 mL
제조사 Dyne Bio



UltraGRO™-Advanced / UltraGRO™-PURE Cell Culture Supplement


UltraGRO™-Advanced / UltraGRO™-PURE meets your need for a consistent, commercial-scale, and reliable human protein based cell culture supplement that can support your cell production from research through to clinical trial use. UltraGRO™-Advanced / UltraGRO™-PURE contains abundant growth factors and cytokines necessary for cell growth and proliferation to replace fetal bovine serum (FBS) for growing Adipose-Derived (AD), Bone Marrow (BM) or Umbilical Cord (UC) Mesenchymal stem cells (MSCs). Growth kinetics for MSCs expanded in 5% UltraGRO™-Advanced / UltraGRO™-PURE containing medium are comparable to cultures grown in medium supplemented with 20% FBS. UltraGRO™-Advanced / UltraGRO™-PURE grows cells quicker and safer, lowering your costs per volume of cells grown.



UltraGRO™-Advanced / UltraGRO™-PURE Safe Material


UltraGRO™-Advanced / UltraGRO™-PURE is derived from normal human platelets collected at North American blood centers. Each platelet unit has been tested and approved for transfusion use. UltraGRO™-Advanced / UltraGRO™-PURE is manufactured from pooled multiple single donor units in large batch sizes. Replacing FBS with UltraGRO™-Advanced / UltraGRO™-PURE allows for production of functional mesenchymal stem cells without the risk of xenogeneic immune reactions, transmission of bovine prions, and viral pathogens. The US FDA is moving towards adopting European guidelines requiring that bovine materials be removed from culturing media for any therapeutic product containing cultured cells, which makes UltraGRO™-Advanced / UltraGRO™-PURE an attractive alternative for the production and manufacturing processes. All UltraGRO™-Advanced / UltraGRO™-PURE lots are tested for pathogens according to FDA guidelines.




  • Cost-effective, non-xenogeneic / serum substitute
  • Natural source and natural signal for cell growth
  • Abundant growth factors / cytokines / proteins that maximize MSC growth
  • Ideal in vivo environment for cell culture
  • Lot to lot consistency
  • Extended storage for without losing potency
  • Research grade and GMP grade available
  • Replace up to 20% FBS with only 5% UltraGRO™-Advanced / UltraGRO™-PURE
  • Better performance in primary and expansion cultures
  • Shorten population doubling times (20~30 hrs)
  • Lower cost per million cells produced
  • No adhesion factors needed
  • Reproducible cell culture results
  • From pre-clinical to clinical trial with the same supplement
  • No heparin required in UltraGRO™-Advanced
  • Drug Master File is available for UltraGRO™-Advanced / UltraGRO™-PURE
  • 100% xeno-free in UltraGRO™-PURE

Clinical Use

At present, the rapid advancement in development of biopharmaceuticals, cellular therapy, and biologics is forcing the industry to seek cell culture media to be animal proteins free, serum-free, and cost effective. UltraGRO™-Advanced is used as a manufacturing component in the generation of human mesenchymal stem cells in 4 clinical trials (phase I) in indications including Crohn’s disease, graft versus host disease, degenerative disc disease, and chronic pancreatitis.

  • 4 Pre-clinical trials
  • 4 Phase I clinical trials


Replace 20% FBS with Only 5% UltraGRO™-Advanced / UltraGRO™-PURE

Growth Kinetics with UltraGRO™ Supplemented Medium for hMSC Expansion




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