Dyne Bio Inc. has developed a new food processing enzyme, β-agarase, from Streptomycescoelicolor which is soil microorganism.
In general, Streptomyces coelicolor is an actinomyces which forms a colony and is structurally
similar to fungi. Actinomycetes are well known for industrial strains producing industrial enzymes and antibiotics,
etc.
However, we succeeded in producing β-agarase and it has been approved for new food additive by
Ministry of Food and Drug Safety (MFDS) in Rep. of Korea.
We developed new manufacturing process of neoagaro-oligosaccharides (Dyne-NAO),
a new bioactive compound, by hydrolyzing the specific binding of agar using microbial enzyme
β-agarase.
Technology
Certification
β-agarase :
- New food additive approved by the Ministry of Food and Drug Safety
(Registration No.: 201833248; Registration Date: November 1, 2018)
- FDA GRAS (Generally Recognized As Safe) (Registration No. GRN 1109)
Thesis
Safety evaluation of β-agarase preparations from Streptomyces coelicolor A3(2). Regulatory Toxicology and Pharmacology. 101, 142-155, 2019.
Non-targeted metabolomics unravels a media-dependent prodiginines production pathway in Streptomyces coelicolor A3(2). PLoS ONE. 13(11): e0207541, 2018.
